Both
diabetes mellitus (DM) and anemia are prevalent around the world. The
possibility of these two diseases co-existing is also very high. Glycosylated
hemoglobin (HbA1c) is used to diagnosed and monitor DM. Incorrect measurements
of HBA1c will cause patients to be misdiagnosed as DM or to follow-up DM
patients incorrectly. Conditions affecting the turnover of erythrocytes may
cause inaccurate HBA1c measurement. In this study, a case of a 33-year-old
patient diagnosed with Type 1 DM due to hemolytic anemia, which was
misdiagnosed due to falsely low HBA1c value, and an 18-year-old patient
misdiagnosed as DM due to falsely high HBA1c value stemming from iron
deficiency anemia are presented. The reliability of HBA1c in the diagnosis and
follow-up of DM is discussed.
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