Chronic pancreatitis is characterized by persistent
morphological and functional changes leading to varying degrees of pancreatic
fibrosis and endocrine/exocrine failure. The most common causes of newly
diagnosed chronic pancreatitis in developed countries and the elderly are
alcohol abuse, obstructive pancreatitis caused by ampullary tumors or
carcinoma, and pancreatic duct stones. In chronic pancreatitis, even if the
underlying cause is eliminated, the process may slow down, but the
deterioration of pancreatic function continues. Treatment is aimed at managing
complications and alleviating symptoms.
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