Juvenile Myoclonic Epilepsy is one of the most common forms
of generalized epilepsy. The onset of seizures usually occurs in adolescence.
The most important sign of the disease are myoclonic seizures. Generalized
tonic clonic and absence seizures may be observed. Generalized 3–5.5-Hz
spike-wave and polyspike-wave are seen on EEG. No abnormality is expected on
brain magnetic resonance imaging. Sodium valproate is considered the first
choice drug for treatment. Due to teratogenicity risk of valproate, it is not
recommended for girls of childbearing potential and alternative medicine
treatments are recommended. Seizure control is often achieved with appropriate
medication and lifestyle recommendations. Progressive myoclonic epilepsies
should be investigated in case of resistance to seizure medication and
cognitive decline. Treatment is often considered lifelong.
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