Pharmacogenetics Of Antidepressants: Overview Of Dosing Strategies In Major Depressive Disorder
Major depressive disorder
is one of the most common psychiatric illnesses worldwide and has low recovery
rates. Clinical evidence has suggested that individualized treatment based on
pharmacogenetic data in antidepressant users may increase treatment success.
Therefore, in this chapter, we focused on the effects of genetic variations in
terms of therapeutic response and dose modifications on major depressive
disorder patients using selective serotonin reuptake inhibitors, serotonin-norepinephrine
reuptake inhibitors, tricyclic antidepressants, and monoamine oxidase
inhibitors.
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