Kenevir (Cannabis)

Yayın Yılı: 2024
Sayfa Sayısı: 237-244
Kitap Dili : Türkçe

Anahtar Kelimeler


It has been shown that cannabis can be associated with cancer and inflammation through the cannabinoids it produces, and can also be used in the treatment of a number of cancer-related symptoms such as pain, anorexia, cachexia, nausea, vomiting, depression and anxiety. Endocannabinoids, cannabinoid active metabolites and receptors have been shown in macrophages, lymphocytes, dendritic cells, monocytes and basophils, suggesting that cannabinoids have a regulatory role on the inflammatory system and are associated with cell proliferation, apoptosis and cell migration through regulation of the inflammatory process. Later studies have shown that cannabis is associated with glioblastoma multiforme, colon, breast, lung, prostate and pancreatic cancer. In addition, cannabinoids have been shown to be involved in pain modulation through specific CB1 and CB2 receptors as well as G protein-coupled receptor 55 (GPCR55), opioid and seretonin receptors. Chemotherapy-induced nausea and vomiting, anxiety, depression, anorexia and cachexia have also been found to be associated with common problems in cancer patients.

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