Infectious diseases are the leading cause of death
worldwide. Resistance to antibiotics used to treat them has become a global
problem. Today, the clinical effectiveness of many available antibiotics
against resistant pathogens is threatened. Marine organisms are rich sources of
bioactive substances or newly structured metabolites. Primary and secondary
metabolites produced by these organisms constitute the area of greatest
interest to the pharmaceutical industry today. Screening of compounds and extracts isolated from different
natural sources is a common way to find biologically active metabolites. Many
studies have reported that algae and its metabolites, as natural resources, are
preferred as a rich source for the development of various nutritional,
industrial and medical products (Borowitzka 1995; Volk & Furkert, 2006;
Evrim et al. 2010). Industrial and technological developments have significantly
increased pollution, and therefore the density and diversity of carcinogenic
substances that pose a threat to human health have also increased. Since the
mid-20th century, it has become necessary to determine the genotoxicity of
every newly detected substance (Al-Haj et al., 2009).
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