Methanol (CH3OH) is among the toxic alcohols that are used as industrial agents and house holds. Although methanol itself is not toxic, its metabolites are highly toxic agents. Both formaldehyde and formic acid are responsible for methanol poisoning (MP) that can lead to hemodynamic instability, blindness, and mortality. Methanol poisoning can cause severe cellular dysfunction mainly due to accumulation of organic acids including formic acid and their anions produced by its metabolism. This chapter begings with etiology, epidemiology and pathophysiology of MP. Diagnosis, manaegment, prognosis and complications of MP are also addressed in the light of the current literature.
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